Drug Reference

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Sodium Bicarbonate Oral tablet

Additional titles for this drug

Sodium Bicarbonate 325mg Tablet, Sodium Bicarbonate 650mg Tablet

What is this medicine?

SODIUM BICARBONATE (SOE dee um; bye KAR bon ate) is an antacid. It is used to treat acid indigestion and heartburn caused by too much acid in the stomach.

How should I use this medicine?

Take this medicine by mouth. Dissolve it in a glass of water before taking. Do not take tablets whole. Follow the directions on the package label. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 60 years old may have a stronger reaction and need a smaller dose.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • confusion

  • dizziness

  • muscle pain

  • nausea, vomiting

  • seizures

  • swelling of the feet and legs

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • bloating and stomach gas

  • increased thirst

  • stomach cramps

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • ammonium chloride

This medicine may also interact with the following medications:

  • antibiotics like ciprofloxacin, doxycycline, tetracycline

  • aspirin and aspirin-like medicines

  • delavirdine

  • ephedra, Ma Huang

  • itraconazole, ketoconazole

  • lithium

  • methenamine

  • norfloxacin

  • quinidine

  • quinine

  • stimulants like amphetamine, dexmethylphenidate, and others

  • tolmetin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • Cushing's syndrome

  • heart problems

  • kidney disease

  • low levels of calcium or potassium in the blood

  • low salt or sodium diet

  • stomach ulcer

  • an unusual or allergic reaction to sodium bicarbonate, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Do not take this medicine for more than 2 weeks unless your doctor directs you to. See your doctor if your symptoms return. You may have a serious medical condition.

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Blue Ridge Pharmacy
2601 Blue Ridge Road
(Across from Rex Hospital)
Raleigh, NC 27607

Ph. 919-781-7986
Fx. 919-781-1833

Pharmacy Hours:

Monday - Friday:
8:30 am - 7 pm
Saturday: 9 am - 3 pm
Sunday: Closed
*Walk-in flu shots available daily (except Tues) 11am-4pm! We file Medicare/BCBSNC.

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