Drug Reference

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Cyclobenzaprine Hydrochloride Oral tablet

Additional titles for this drug

Cyclobenzaprine Hydrochloride 10mg Tablet, Cyclobenzaprine Hydrochloride 5mg Tablet, Fexmid 7.5mg Tablet, Flexeril 10mg Tablet, Flexeril 5mg Tablet

What is this medicine?

CYCLOBENZAPRINE (sye kloe BEN za preen) is a muscle relaxer. It is used to treat muscle pain, spasms, and stiffness.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. If this medicine upsets your stomach, take it with food or milk. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • chest pain

  • fast heartbeat

  • hallucinations

  • seizures

  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • cisapride

  • droperidol

  • flecainide

  • grepafloxacin

  • halofantrine

  • levomethadyl

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • nilotinib

  • pimozide

  • probucol

  • sertindole

This medicine may also interact with the following medications:

  • abarelix

  • alcohol

  • contrast dyes

  • dolasetron

  • guanethidine

  • medicines for cancer

  • medicines for depression, anxiety, or psychotic disturbances

  • medicines to treat an irregular heartbeat

  • medicines used for sleep or numbness during surgery or procedure

  • methadone

  • octreotide

  • ondansetron

  • palonosetron

  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

  • some medicines for infection like alfuzosin, chloroquine, clarithromycin, levofloxacin, mefloquine, pentamidine, troleandomycin

  • tramadol

  • vardenafil

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease, irregular heartbeat, or previous heart attack

  • liver disease

  • thyroid problem

  • an unusual or allergic reaction to cyclobenzaprine, tricyclic antidepressants, lactose, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Check with your doctor or health care professional if your condition does not improve within 1 to 3 weeks.

You may get drowsy or dizzy when you first start taking the medicine or change doses. Do not drive, use machinery, or do anything that may be dangerous until you know how the medicine affects you. Stand or sit up slowly.

Your mouth may get dry. Drinking water, chewing sugarless gum, or sucking on hard candy may help.

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Blue Ridge Pharmacy
2601 Blue Ridge Road
(Across from Rex Hospital)
Raleigh, NC 27607

Ph. 919-781-7986
Fx. 919-781-1833

Pharmacy Hours:

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8:30 am - 7 pm
Saturday: 9 am - 3 pm
Sunday: Closed
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