Drug Reference

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Hydrocortisone Rectal cream

Additional titles for this drug

Anusol HC 2.5% Rectal Cream, Proctocort 1% Rectal Cream, Proctocream-HC 2.5% Rectal Cream, Procto-Kit 1% Rectal Cream, Procto-Kit 2.5% Rectal Cream, Procto-Pak 1% Rectal Cream, Proctosol-HC 2.5% Rectal Cream, Proctozone-HC 2.5% Rectal Cream

What is this medicine?

HYDROCORTISONE (hye droe KOR ti sone) is a corticosteroid. It is used to decrease swelling, itching and pain that is caused by minor skin irritations or hemorrhoids.

How should I use this medicine?

This medicine is for rectal use only. Do not take by mouth. Do not apply to your eye. Follow directions on the prescription label. Wash your hands before and after use. Apply a thin film to the affected area. Do not use on healthy skin or over large areas of skin. Do not cover with a bandage or dressing unless your doctor or health care professional tells you to. If you are to cover the area, follow the instructions carefully. Covering the area can increase the amount that passes through the skin and increases the risk of side effects. Do not use your medicine more often than directed. It is important not to use more medicine than prescribed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. If applying this medicine to the diaper area of a child, do not cover with tight-fitting diapers or plastic pants.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • burning or itching of the skin

  • dark red spots on the skin

  • infection

  • lack of healing of skin condition

  • painful, red, pus-filled blisters in hair follicles

  • thinning of the skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dry skin, irritation

  • unusual increased growth of hair on the face or body

What may interact with this medicine?

Interactions are not expected. Do not use any other skin products on the affected area without telling your doctor or health care professional.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from heat and freezing. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • an unusual or allergic reaction to hydrocortisone, corticosteroids, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better after a few days.

If you get any type of infection while using this medicine, you may need to stop using this medicine until your infections clears up. Ask your doctor or health care professional for advice.

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Blue Ridge Pharmacy
2601 Blue Ridge Road
(Across from Rex Hospital)
Raleigh, NC 27607

Ph. 919-781-7986
Fx. 919-781-1833

Pharmacy Hours:

Monday - Friday:
8:30 am - 7 pm
Saturday: 9 am - 3 pm
Sunday: Closed
*Walk-in flu shots available daily (except Tues) 11am-4pm! We file Medicare/BCBSNC.

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